For dogs: 1.0 ml of the drug contains the following ingredients: imidacloprid - 100 mg, ivermectin - 25 mg. Additional ingredients: N-methylpyrrolidone, citric acid, PEG-400. The drug is highly effective against ectoparasites such as fleas, skin mites (otodectosis, demodicosis, etc.), and endoparasites: nematodes, dirofilaria (effective against larvae of the L3 and L4 stages). The drug contains imidacloprid, which acts on the receptors of the nervous system of ectoparasites, disrupting the transmission of nerve impulses, which leads to paralysis and subsequent death of the parasite. Imidacloprid does not penetrate the blood-brain barrier and, accordingly, does not reach the central nervous system of patients. Ivermectin has an antiparasitic effect on larval and mature forms of nematodes. Indications for use: Prevention and treatment of animals with fleas, intestinal nematodes, scabies mites (Otodectes cynotis, Notoedres cati, Sarcoptes canis), demodicosis, as well as prevention of dirofilariasis (effective against L3 and L4 larval stages).